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In 1955, Ontario centers started trading semen across provinces, and by 1959, Canadian semen reached the University of Munich in Germany

In parallel, gut-resident T cells conditioned by the microbiota (for instance, pro-inflammatory Th17 cells versus anti-inflammatory regulatory T cells) can traffic to the CNS [38]

H., & Kim, B

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These alterations not only enable OC cells to survive and proliferate, but they also endow them with the ability to metastasize, acquire resistance to chemotherapy 6 , maintain a cancer stem cell phenotype 7 , and evade the effects of anti-tumor immune defense mechanisms 8