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In contrast, the AIM-HIGH (Atherothrombosis intervention in metabolic syndrome with low HDL/high triglycerides: impact on global health outcomes) trial, which examined the incremental effect of extended-release nicotinic acid (1.5-2 g/day) on 3,414 patients who had established CVD and atherogenic dyslipidemia and were treated with simvastatin (+/- ezetimibe), provided disappointing results

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In 1964 the United States Surgeon Generals Report on Smoking and Health likewise began suggesting the relationship between smoking and cancer, which confirmed its suggestions 20 years later in the 1980s

Its impressive to see the more than 30% decline in smoking among men there in the past 15 years and you see similar trends among men in many countries around the world

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