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Results Inhibition of -Oxidation Alleviates ER Stress in Metabolically Active Cell Types We have previously shown in the liver and in hepatoma cells in vitro that inhibiting -oxidation diminishes ER stress signaling (Tyra et al., 2012)

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doi: 10.1371/journal.ppat.0020092, 12 DunnO

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In particular, hemocompatibility of blood-contacting devices is tested in vitro in accordance with the ISO standard 10993-4 guidelines, and this testing comprises evaluation of thrombosis, the blood coagulation system, the complement system, and multiple effects on platelets and leukocytes [464]