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As a result, patients may experience a significant burden from deficiencies

Production of these reactive oxygen species is known to occur as a result of a few different mechanisms: 1) mitochondrial origin in which free radicals either escape scavenging enzymes or develop due to an error in oxidative processes, 2) inside the capillary endothelium where a hypoxic and reoxygenation process is created during intense exercise as well as during various types of cardiovascular disease, and 3) an oxidative burst from inflammatory cells which are commonly mobilized as a result of the muscle or tissue damage which is well-documented with extended or eccentric-based exercise[1]

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Vitamin B12 plays a vital role in producing red blood cells and maintaining effective oxygen transport

Other treatments, not part of this study, included shockwave therapy, home training, corticosteroid injections, surgery, and exercise programs

Heavy smokers and drinkers can also have low levels of B12