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Cyanocobalamin, vitamin B12 preparations containing benzyl alcohol should be avoided in premature neonates because benzyl alcohol has been associated with gasping syndrome, a potentially fatal condition characterized by metabolic acidosis and CNS, respiratory, circulatory, and renal dysfunction

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However, it is important to be aware of the molecules safety profile and potential side effects before administering it to test subjects

Those who follow a vegetarian or vegan diet are particularly prone to vitamin B-12 deficiency, as are those with a condition known as Pernicious anemia which affects B-12 absorption in the gut