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However, consistent with current findings, probably the accumulation of 1,3-BPG in patients with PGK1 deficiency might be a key contributor to promote the increased of the highly reactive intermediate metabolite cyclic 1,3-phosphoglycerate, contributing to exacerbated DA neuron cell death in PD

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Evidence from case series and small cohort studies conducted in the USA and Canada supports this notion, demonstrating favorable outcomes for HIV-infected patients, with survival rates comparable to those of their HIV-uninfected counterparts for up to five years post-transplant (5961)

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