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Unfortunately, the same chemical property that enhances bioavailability of drugs may also make renal excretion difficult, because clearance by the kidney requires that these drugs be made more hydrophilic so that they can dissolve in the aqueous urine

However, if NAC was given four hours after the overdose, there was no reduction in liver toxicity, and 80% of the mice died

Optimizing nutrition for pediatric cancer patients and survivors

K., Crabb, J

ArticlePubMedPMC 81

Nevertheless, it was assumed that the spectrum of compounds evaluated was sufficiently broad to encompass the main non-regulated mycotoxins of relevance