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FIGURE 4 2.4 The anti-inflammatory activity of the compounds Initial screening of the nine newly synthesized compounds for anti-inflammatory activity was performed using LPS (1 g/mL)-stimulated RAW264.7 macrophages over 24 h ( 2 S confers organ protection through: (i) Suppression of NF-B nuclear translocation and downstream pro-inflammatory gene expression

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Kawaguchi Y, Newhook TE, Tran Cao HS, Tzeng CD, Chun YS, Aloia TA, Dasari A, Kopetz S , Vauthey JN