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One molecule, many derivatives: a never-ending interaction of melatonin with reactive oxygen and nitrogen species

3h, i of mice treated with 100 nmol kg 1 MK-801 ( n = 8 mice and n = 4 cages), 100 nmol kg 1 GLP-1 ( n = 8 mice and n = 4 cages), 100 nmol kg 1 GLP-1MK-801 ( n = 8 mice and n = 4 cages) or vehicle (isotonic saline, n = 8 mice and n = 4 cages) for 5 days

Neurobiol Aging (2016) 43:112

& Grossberg, G

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However, xenobiotics that cause liver enlargement primarily by hepatocellular hypertrophy may also produce transient (phenobarbital-like xenobiotics) or sustained (WY-14,643) hepatocyte proliferation