Berberine reduces collagen deposition and renal tubular necrosis and cystic dilation in a cisplatin-induced renal injury rat model by inhibiting SIRT2
4 Role of Nuclear Factor Erythroid 2-Related Factor 2 in Breast Cancer Resistance Nrf2 is a leucine zipper protein transcription factor that positively regulates the expression of antioxidant genes, such as GPX4, HO-1, SLC7A11, and NAD(P)H quinone oxidoreductase (Qiao et al., 2020)
Moreover, HO-1 promotes heme breakdown, which increases intracellular free iron levels and expedites the ferroptotic process (Sun et al
The effects of L-carnitine supplementation on inflammatory factors, oxidative stress, and clinical outcomes in patients with sepsis admitted to the intensive care unit (ICU): study protocol for a double blind, randomized, placebo-controlled clinical trial
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