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Reducing Beclin-1 rates in HT29 cells resulted in a decline in BA-induced LC3-II lipidation

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Pharmaceutical blockade of Na v 1.7 using a selective blocker PF-05089771 or gastrodin (an active bioactive component of traditional Chinese medicine, Gastrodia, which is widely used for analgesic) as well as gene silencing of Na v 1.7, greatly reduced the vincristine-induced hyperexcitability in cultured DRG neurons and reversed vincristine-induced mechanical allodynia in rats (Fu and Zhu, 2021