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However, the fact that no effect was found in rabbits injected intravenously with 3 mg/kg suggests that human exposure to acrolein is unlikely to affect the developing embryo (section 7.5)

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Patil SP, Wang J, Song Y, Noone S, Yang N, Wallenstein S et al (2011) Clinical safety of Food Allergy Herbal Formula-2 (FAHF-2) and inhibitory effect on basophils from patients with food allergy: extended phase I study

However, one study investigated non-BRCA1/2 gene abnormalities, and found that they confer sensitivities to PARP inhibition comparable to those observed with BRCA1/2 mutations (147)