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It may be because of the short treatment course in our study (50 2 days) or continuing of FM medications such as duloxetine or tricyclic antidepressants in the study time which could attenuate the vitamin B12 effect

Notably, compound 1d exhibited the most potent activity against Escherichia coli and Staphylococcus aureus with MIC ranges of 31.3125.0 g/mL and against Pseudomonas aeruginosa with MIC ranges of 375.0500.0 g/mL

Wang, C., Tao, Q., Wang, X., Wang, X

Functional assessments such as creatine loading tests and advanced tissue imaging (e.g., magnetic resonance spectroscopy) may offer dynamic, patient-specific evaluations of mitochondrial responsiveness and guide individualized preventive protocols

It is recognized as the standard treatment for acetaminophen overdose and has been used as a mucolytic drug since the 1960s [1]

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