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10.1126/science.aar3932 Science 259 WangX

doi: 10.1111/j.1365-2133.2012.11197.x

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During the development of kidney stones, risk factors such as CaOx crystals, urine microenvironmental changes, and selenium deficiency induce ferroptosis through mechanisms such as oxidative stress, ERS, and autophagy

It may be obtained through many chemical procedures of thioctic acid and stops the important activities of R-ALA, e.g., their interaction with genes, enzymes and proteins [23]