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The synthesis of 5-HT is initiated by the rate-limiting enzyme tryptophan hydroxylase (TPH), which exists in two isoforms: TPH1, predominantly expressed in the gut enterochromaffin cells, and TPH2, primarily found in the central nervous system (CNS) (Imamdin and Van Der Vorst, 2023

J Biomol Screen 18, 851867

In one example, the cohesin loader was shown to facilitate transcription elongation by releasing paused RNA polymerase II through interaction with the super elongation complex 49

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Antioxidants (Basel) 13, 394.Google Scholar Maldonado, E, Morales-Pison, S, Urbina, F et al

Clinical studies in human preterm (Valaes et al., 1994), full-term (Martinez et al., 1999), and near-term newborns (Kappas et al., 1995) showed that SnMP substantially moderated the course of hyperbilirubinemia, significantly decreasing the mean peak incremental TB concentration (Valaes et al., 1994), phototherapy use (Valaes et al., 1994