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GHK-Cu increases collagen synthesis by 70% in human fibroblasts, surpassing vitamin C (50% increase) and retinoic acid (40% increase)

In addition, inhibition of Dhodh in tumor cells can reduce CDP-choline levels and the phosphatidylcholine (PC) synthesis of CDP-choline-dependent Kennedy pathway, promote CD8 + T cell infiltration and enhance the antitumor activity of PD-1 blockade in female mouse models [235]