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While these effects are not evidence of addiction, they do indicate that the brain and nervous system can adapt to long-term SSRI use

[Updated 2023 Jul 24]

Advances in gene therapy and small molecules able to upregulate EAAT2 expression are under investigation as potential intervention 35 that could mitigate oxidative stress and excitotoxicity, reducing neuronal damage

They can come up with a plan for you to lower your dosage slowly over time until it is safe for you to stop the medication completely and switch to escitalopram

Figure 3 Construction of GSTM1 and GSTT1 knockout mice To further investigate the mechanism by which GSTM1 and GSTT1 are involved in the pathogenesis of acute kidney injury (AKI), we successfully constructed mice with GSTM1 and GSTT1 knockout (GSTM1-KO and GSTT1-KO) using CRISPR-Cas9 technology