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Cell 179(2):312339 Lukiw WJ, Zhao Y, Cui JG (2008) An NF-B-sensitive micro RNA-146a-mediated inflammatory circuit in Alzheimer disease and in stressed human brain cells

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Kidney Dysfunction and Disease High Hcy levels also impact the kidneys by breaking down glutathione, which harms kidney function

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AD brains exhibited a notable elevation of oxidative biomarkers, including 8-hydroxydeoxyguanosine (8-OHdG) and 8- hydroxyguanosine (8-OHG) in both mitochondrial and nuclear DNA (Wang, 2020)