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2.3 Data extraction and quality assessment Data extraction was performed using an extraction table that focussed on study characteristics (first author, year of publication, and study design), participant characteristics (number, subgroup, age), outcomes (levels of TPOAb, TgAb, and TSH), and adjusted matching factors

Poor Glutathione Status and Difficulty With TTFD In someone who has poor glutathione (GSH) status, they might theoretically be less able to cleave thiamine from TTFD

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The reduced form is the most bioavailable and therefore the most effective