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[9] [28] [29] Researchers developed a prodrug, HU6, which is metabolized to DNP in the liver to provide more stable blood concentrations

[PUBMED Abstract] Pui CH, Sandlund JT, Pei D, et al.: Improved outcome for children with acute lymphoblastic leukemia: results of Total Therapy Study XIIIB at St Jude Children's Research Hospital

Nature 384:256258

Trials are underway evaluating safety and dose ranges for peptides targeting endometrial repair and ovarian reserve support, with early phase data reporting on tolerability and local tissue response