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During stressful circumstances, the distinctive oxidative burst due to catalytic activities of specified ROS-generating enzymes such as nicotinamide adenine dinucleotide phosphate (NADPH) oxidases or cell wall peroxidases (PODs) lead to vast ROS accumulation in the affected cells [91]

Similar content being viewed by others Introduction Ischemic stroke (IS) results from the abrupt cessation of blood supply to the brain, resulting in neuronal death and subsequent neurological deficits

On the other hand, alkaloids from plants often target cell division and transcriptional machinery

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Similarly, the involvement of oxidative stress in sepsis, which disrupts redox signaling, leading to molecular damage, has been highlighted (172)