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Excess SCFAs that are not metabolized by IECs are transported via the hepatic vein to the liver, where they can be incorporated as precursors into gluconeogenesis, lipogenesis, and cholesterologenesis [62]

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Therefore, the aim of the present study was to assess the effect of L-carnitine on Doxorubicin and Cyclophosphamide induced chemobrain in rats in addition to study the possible oxidative stress, inflammatory response, synaptic plasticity, liver-brain and kidney-brain related mechanisms