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The companys lead candidate, PN6047 has been shown to effectively reduce neuropathic pain in preclinical studies

10.1182/blood.2020007233 123 StelmachP.TrumppA

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Abstract Cellular hypoxia occurs when the demand for sufficient molecular oxygen needed to produce the levels of ATP required to perform physiological functions exceeds the vascular supply, thereby leading to a state of oxygen depletion with the associated risk of bioenergetic crisis

Part of the antioxidant capacity of serum is due to the presence of GSH and the reduced capacity could be associated with a general reduction in GSH due to its conjugation with NAPQI