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Involvement of cannabinoid signaling in vincristine-induced gastrointestinal dysmotility in the rat

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10.3892/mmr.2018.9443 Mol Med Rep

253,279,280 Uric acid can enhance AKT phosphorylation, which subsequently leads to PRAS40 phosphorylation with the activation of mTOR, 281 resulting in the inhibition of autophagy, as well as inhibiting AMPK phosphorylation

It also enhances our understanding of the pathophysiology of depression and supports the development of more precise and holistic treatment strategiesreflecting the core principle of TCM's "holistic view." Continued research in this area holds the potential to improve therapeutic outcomes for depression and significantly enhance patients quality of life

10.1016/j.colsurfa.2021.128044 227 UtzeriG.VerissimoL.MurtinhoD.PaisA