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The specific mechanism remains to be elucidated

Urinalyses with careful microscopic examination and renal function tests should be performed during therapy, particularly for those patients with impaired renal function

Furthermore, complicated similarity descriptors are hard to manage by the experimental pharmaceutial chemists and of little use if the scaffold hopping campaign starts from a single active compound only

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Next, we performed a time course assay of liposome leakage and further confirmed that MeCbl (1 M) pretreatment sustainably inhibited liposome leakage (Fig

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