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One major limitation is the incomplete knowledge of the metabolic pathways and transformations that polyphenols undergo after ingestion, particularly due to interactions with the gut microbiome and the formation of diverse metabolites whose biological activities are not well characterized (119)

In a diabetic retinopathy model, AST treatment elevated the levels of the antioxidant enzyme heme oxygenase-1 (HO-1) and preserved homeostasis for retinal ganglion cells (Yoshihisa et al., 2014)

Neurology(R) neuroimmunology Neuroinflamm

IKK-beta-mediated myeloid cell activation exacerbates inflammation and inhibits recovery after spinal cord injury

3.8 Kidneys SGD can promote the spontaneous excretion of stones, with 91% of small stones (5 5 mm and below) and 33% of medium-sized stones (6 10 mm and below) being discharged (Washizuka et al., 1983)

The gastrointestinal actions of FAHF led to their assessment as a food allergy treatment strategy