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the liver) show that ceramide accumulation or depletion is sufficient to regulate Srebf1 gene expression, as well as sterol response element (SRE)-mediated transcriptional targets (71, 72)

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Transient elastography (TE) with controlled attenuation parameter and laboratory-based risk scores (NFS, FIB-4) were the main diagnostic workup tools for risk stratification Results: After preselection based on questionnaire information NAFLD still accounts for one-fifth of patients in the liver outpatient service