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By elevating oxidative stress, NRF2 degradation induces apoptosis in cancer cells and increases their sensitivity to chemotherapeutic agents, thereby enhancing the effectiveness of chemotherapy [95]

Cullell N, Soriano-Trraga C, Gallego-Fbrega C, Crcel-Mrquez J, Torres-guila NP, Muio E, Lleds M, Lluci-Carol L, Esteller M, Castro de Moura M, Montaner J, Fernndez-Sanls A, Elosua R, Delgado P, Mart-Fbregas J, Krupinski J, Roquer J, Jimnez-Conde J, Fernndez-Cadenas I (2022) DNA methylation and ischemic stroke risk: an epigenome-wide association study

Antioxid Redox Signal 14: 14211424, 2011

Personal neoantigen vaccines induce persistent memory T cell responses and epitope spreading in patients with melanoma

Abstract Ferroptosis is a form of regulated cell death driven by iron-dependent lipid peroxidation, which plays a pivotal role in regulating the inflammatory-immune microenvironment of central nervous system (CNS) diseases