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Common Side Effects Injection-site reactions: Discomfort, redness or soreness at the site can occur

Research demonstrates that copper ions can inhibit up to 90% of type 1 5-alpha reductase at specific concentrations

These substances are often substances produced by the body (metabolites) that cannot be removed properly due to the impaired function of the kidneys

In: StatPearls

In estrogen biology, GSTM1 and GSTT1 serve a specific and critical function: they conjugate the reactive quinone metabolites produced when catechol estrogens particularly 4-OHE2 (4-hydroxyestradiol) are not rapidly methylated by COMT or sulfated by SULT1A1 and instead undergo further oxidation: The oxidation cascade: CYP1B1 converts estradiol to 4-OHE2 if COMT and SULT1A1 cannot clear 4-OHE2 quickly, one-electron oxidation produces 4-OHE2 semiquinone two-electron oxidation produces 4-OHE2 quinone (4-OHE2-Q)

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