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ArticlePubMed 21

Curcumin (200 mg/kg) significantly ameliorated brain injury and neurological deficits in rats subjected to middle cerebral artery occlusion by upregulating autophagy-related proteins p-Akt and p-mTOR, while downregulating autophagy-associated proteins LC3-II/LC3-I and inflammation-related proteins IL-1, TLR4, p-38 and p-p38

Studies have shown that propofol can increase the levels of ferritin heavy chain-1 (FTH1), xCT, or GPX4, improve the antioxidant capacity of cardiomyocytes via iron level reduction and inhibit cell ferroptosis through the AKT/P53 signalling pathway (Li et al., 2022)

Shimazu T, Hirschey MD, Newman J, He W, Shirakawa K, Le Moan N, et al

Because skin cells take roughly 28 to 40 days to turn over, you are essentially "feeding" the new cells that have not yet reached the surface