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Typical usage levels in cosmetics are usually low and in the range of 0.015 - 2.3%

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10.1523/JNEUROSCI.21-10-03322.2001 125 WangY.JiaT.FengY.LiuS.ZhangW.ZhangD.et al (2021a)

Rather than using a scalpel, scars can be created by using a cryoprobe to apply extreme cold or a radiofrequency device that applies heat

Cramer T, Yamanishi Y, Clausen BE, Frster I, Pawlinski R, Mackman N, Haase VH, Jaenisch R, Corr M, Nizet V, Firestein GS, Gerber HP, Ferrara N, Johnson RS