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Animal model studies have preliminarily revealed that Clostridium colonization can curtail the overgrowth of pro-inflammatory microbiota, restore the intestinal mucosal barrier, and limit systemic translocation of bacterial LPS, ultimately reestablishing gut microbial homeostasis (206, 207)

[64] did not improve outcomes over conservative care, suggesting that extremely high concentrations may not enhance efficacy

Molecular Vision , 17 , 3180-3190

Regular monitoring of fasting glucose, fasting insulin, HOMA-IR, and HbA1c is suggested to monitor changes and refine dosing or lifestyle plans

Understanding these factors is crucial before considering the impact of supplements on treatment outcomes

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