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In addition, immunofluorescence analysis indicated an up-regulation of endothelial Platelet Endothelial Cell Adhesion Molecule-1 (PECAM1) expression following exposure to 3R4F, NF and ultralow nicotine cigarettes (Figure 6B)

Furthermore, the LZ motif in OPTN can form a complex with ATG9A vesicles, contributing to the de novo synthesis of autophagosomal membranes independently of the LC3 pathway

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