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Visible body composition improvements typically take 8-12 weeks of consistent use

Previous work has reported relatively increased Firmicutes and Proteobacteria and decreased Bacteroidetes in mice on an HFD, regardless of concomitant obesity (weight gain was minimized using a RELM knockout mouse 78 ) 78,79

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Development was discontinued because the Phase IIb trial of 536 subjects over 24 weeks failed to meet its primary efficacy endpoint

Neural tube defects include conditions such as anencephaly and spina bifida, which are usually fatal birth defects that happen when the baby's neural tube doesn't properly close

Sources Lovelace, B., Jr., McLaughlin, E., & Heikkila, A