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doi: 10.1128/jb.141.1.156-163.1980 34 ElkinsJGHassettDJStewartPSSchweizerHPMcDermottTR

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Wingfield et al., 1999)

Plant biotechnology journal 11 , 555563 (2013)

At the 5-year update, the PFS rate was 71 % for the AcalaO arm versus 18 % for CBL+O in patients with del(17p) and/or mutated TP53

And CD4 + CD25 + T cells effectively inhibited colonic effector T cell activity and the production of Th1 (interferon (IFN)-, IL-2) and Th2 (IL-5, IL-13) cytokines in vitro, while the frequency of Treg cells in the inflammatory area increases with the increase of active UC disease activity [68, 69]