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1,18,27 As such, high-concentration DPs can be defined as those that exhibit distinct solution and stability properties, such as high viscosity, particle formation, and opalescence, relative to DPs at low concentrations ( 20 centipoises, cP), the force required to depress a syringe plunger may cause pain for patients and healthcare providers, and it may result in delivering a partial dose through incomplete injection

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This structural feature gives the peptide exceptional stability and resistance to breakdown by digestive enzymes, setting it apart from most other therapeutic peptides