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Ceftriaxone is highly bound to plasma proteins

Mild injection site pain and irritation (also known as a sore arm) are common after receiving many vaccinations, including the influenza vaccine, pneumococcal vaccine, varicella vaccine, and COVID-19 vaccine

No significant lab abnormalities reported in long-term users

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Nasal delivery may be particularly effective in the treatment of neurological diseases due to the direct nose-to-brain pathway