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doi: 10.1248/cpb.c15-00400, 146

It is necessary to expand extensive chronic clinical trials to evaluate the long-term safety, efficacy, and optimal dosing of polyphenols, examine gene-diet and microbiota-polyphenol interactions to elucidate inter-individual variability, develop innovative delivery systems to improve bioavailability and facilitate clinical translation, and clarify potential drug interactions and safety in vulnerable populations

[DOI] [PMC free article] [PubMed] [Google Scholar] 504.Smith C, Gore A, Yan W, Abalde-Atristain L, Li Z, He C, et al

2008;5(5):e105-767 Holm LW

They're simple, but each has a specific role

So knnen die verschiedenen Krankheitszeichen in unterschiedlicher Intensitt und Kombination auftreten je nachdem, welche Bereiche des Zentralen Nervensystems von den MS-bedingten Entzndungsherden bzw