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Frontiers in Pharmacology, August 2018, ePublication

Women, individuals with certain health conditions like obesity or diabetes, and those with a family history of carpal tunnel syndrome are also at an increased risk

First identified as a factor which regulates the expression of the immunoglobulin light chains in B lymphocytes [57] NF-B is also recognized as a sequence-specific transcription factor involved in the activation of an exceptionally large number of genes in response to inflammation, viral and bacterial infections, and other stressful situations requiring rapid reprogramming of gene expression, such as oxidative challenge [54, 55]

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