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Results: DDC mice had increased AST, ALT, bilirubin, bile acids, ductular reaction and macrophage infiltration and reduced hepatocyte mRNA expression of Abcb11, Abcg8, Nr0b2 (SHP), Nr5a2 and Abcc2 mRNA relative to chow fed mice

UPS is involved in all aspects of cellular activity

This was because most of the mice that received 3- and 5-Gy irradiation were dead before 700 days, and only limited breeding space was available

As research advances, these applications could transform how we manage sepsis, ischemia, and other conditions tied to ferroptosis and oxidation

10.1007/s11192-009-0146-3 33