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was supported by the Intramural Research Program of the National Institutes of Health (H.C., ZIAAG000928, 000959, 000945)

2hj), further supporting that MeCbl directly targets GSDME but not upstream events

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Vitamin D plays a role in immune regulation and could also stimulate melanocytes

Oral and topical forms of GSH have shown moderate success in reducing melanin levels with minimal side effects, while intravenous use, though popular, raises significant safety concerns, including risks of anaphylaxis and liver damage

Silent agonists are compounds that bind to the 7nAChR without directly activating the ion channel