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[64] [77] [78] [79] [80] [81] Effectiveness [note 1] case-control study published in August 2021, found that two doses of the BNT162b2 (Pfizer) vaccine had 93.7% effectiveness against symptomatic disease caused by the alpha (B.1.1.7) variant and 88.0% effectiveness against symptomatic disease caused by the delta (B.1.617.2) variant

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Yet, even in the most extensively vaccinated populations, Omicron waves coincided with paradoxical spikes in all-cause mortality

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