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Cycling of erythropoietin levels between extreme levels can lead to vascular remodeling, which may also be related to its cardiovascular effects

doi: 10.3390/ijms19041264 31 WoolardJBevanHSHarperSJBatesDO

Cytoplasmic NADPH generation from the CPS relies upon cytoplasmic ACLY metabolizing CoA and mitochondrial-exported citrate for the generation of oxaloacetate and acetyl-CoA