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Historical literature suggests that 15-40% of untreated individuals will develop tertiary syphilis, which can manifest as destructive cardiac or neurological conditions, severe skin or visceral lesions, or bony involvement

A recent study of college students found that a higher risk for bipolar spectrum disorders is tied to more cannabis-related disruptions in daily life, while experiencing higher levels of natural positive emotions is associated with less frequent cannabis use

They may ask: Your healthcare provider may also ask about behaviors that put you at risk, like drug use or smoking