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Description

OCN, GRP, and MGP are shown separately due to their low sequence homology to other VKDPs in the Gla domain

Food and Drug Administration, Center of Drug Regulation and Research

Although dietary-derived antioxidants, particularly polyphenols, demonstrate robust antioxidant and anti-inflammatory effects in preclinical models, their clinical translation is constrained by significant pharmacokinetic limitations

cGKI-deficient mice are characterized by enhanced eryptosis, anemia, and splenomegaly with accumulation of PS-exposing erythrocytes in the spleen [175]