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Recent spatial metabolomics and single-cell transcriptomics studies by Kumar et al

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The plot displayed the absolute difference between the two methods on the x-axis and their average on the y-axis

Upon entering the cytoplasm of a cell, the pro-drug is de-esterified by one or various intracellular esterases, to release the drug which has at least one carboxyl moiety (COOH) and a by-product (typically ethanol) which contains the hydroxyl moiety (OH)

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