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While mild, transient sleep changes may not require immediate medical attention, certain patterns and associated symptoms warrant prompt communication with your healthcare provider

1.1 Mechanisms of capsaicin regulating energy metabolism 1.1.1 TRPV1-dependent and -independent energy expenditure Capsaicin-induced thermogenesis in adipose tissue is initiated by activation of TRPV1, a Ca 2+ permeable cation channel whose opening elevates intracellular Ca 2+ and triggers downstream kinase signaling (57)

doi: 10.3389/fphar.2023.1327230 Received 24 October 2023 Accepted 05 December 2023 Published 19 December 2023 Volume 14 - 2023 Edited by Amedeo De Nicol, University of Turin, Italy Reviewed by Yuan Liu, Yangzhou University, China Vigyasa Singh, University of Arizona, United States Updates Copyright 2023 Yi, Liu, Yang, Wu, Du and Shen

10.1016/j.jnutbio.2025.109962 129 JianxinC.RuiX.LifangQ