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To define the molecular determinants for the preferential binding to SMRT/NCoR, we solved the crystal structure of SHARP SPOC in complex with 1S5P CTD peptide at a resolution of 1.55 (Fig

Indeed, the global alterations in DNA methylation may result in embryo death and developmental defects (Reik et al., 2001)

LncRNA ZNF593-AS alleviates diabetic cardiomyopathy via suppressing IRF3 signaling pathway

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While CD-fed and HFD-fed recipients in our study did not differ in percent weight gains over the course of the experiment, most likely because HFD intake was limited in duration, obesogenic status (high BMI) and a HFD regimen share common inflammatory pathways