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The incorporation of these technologies is likely to improve cardiovascular medicine and accelerate the change from molecular mechanisms to clinical practice, ultimately realizing the 4P vision of precision medicine: Predictive, Preventive, Personalized, and Participatory

Each mechanism of dysfunction at the pre-synaptic, post-synaptic, and peri-synaptic level offers itself as a target for intervention to improve stabilization, junctional signaling, and synapse integrity [213], potentially even before symptomatic weakness in those with genetic susceptibilities

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Practical takeaway: Treat hydration as one sensible habit among several alongside eating before drinking, pacing your drinks, and tracking time rather than a single fix for any one variable in your BAC estimate

Detailed light conditions are provided in Supplementary Fig

Disposition 40 , 754760 (2012)