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designed a US-triggered MnWO X nanosystem modified with PEG (termed MnWO X -PEG) to endow the capability of GSH-enhanced ROS ( 1 O 2 and OH) production for killing malignant tumors (Figure 6D) ( X -PEG exhibited significantly time-dependent GSH consumption capacity through reducing W 6+ to W 5+ (Figure 6E), cooperating with increased ROS to achieve a powerful inhibition effect on tumors (Figure 6F)

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Your body then has to try to rebuild the glutathione from scratch, which is far less efficient than receiving it intact

Bruni, H.K

Overexpression of human GPX1 modifies Bax to Bcl-2 apoptotic ratio in human endothelial cells